From what I've read and from my personal experience, its the opposite. 5w4s tend to be easier to relate to through their 4 wing and artistic/humanistic traits, but are generally more content being by themselves as they are happy to be in their own world. 5w6s on the other hand, are far less personable and far more detached, sequential, and logical. They deal in math, hard science, and impersonal systems rather than literature and art, making them less relatable to most people. However the 6 wing also causes them to desire acceptance from others resulting in the oft-mentioned "uneasy truce" between the 5w6s' desire to be socially accepted and have companionship and their desire to maintain their independence. So I would say 5w6s are the ones more apt to desire social acceptance and yet less likely to be able to achieve it. I too seem to encounter more 5w6s than 5w4s. 5w4s are generally considered to be the cooler of the two types also as they have the John Lennon's and Tim Burton's, while we have Nietzsche, so in that sense I think this is a good thread to start.
The difference between being a 4 wing and a 6 wing is not being into art/literature vs. being into hard science. It is (more or less) fearing a loss of individulaity and lack of personal significance vs. fearing being disliked and rejected by others. Both in addition to (and not as prominant as) the fear of being incompetent and the tendency to detach and withdraw.
Some Points:
1. Most 5w4's seem to be INTP, which tends to be the most logical of all types because of dominant Ti and a preference for abstraction. So 5w4's are not necessarily less logical.
2. Being logical does
not preclude an interest in art and literature! Whether or not we make decisions guided by them, we all have emotions! Plus, any NT would have the creative proclvities of N, which would help them appreciate the extreme creativity found in these fields.
3. Most great NT novelists were INTJ, and most INTJ's are 5w6.
4. A person
can be into both art and hard science!
Can I just also add that logical =/= sequential. Nor does values-based = holistic. There is a difference between Ti and Te, and Fi and Fe for that matter. This might seem persnickety, but this is not widely known and it leads to a lot of confusion, especially amongst Fi types.
NB. Perhaps there is a correlation of interests with E type/wing. I'm not denying that, but I think this needs to be said. It would be a shame if, say, a 5w6 mistyped themselves as a 5w4 because they thought they "could not be into the arts" if they were 5w6.