I'm closely familiar with a 2w1 sx/sp, and have met someone with 2w1 sp/sx subtype.
One difference that stood out to me is that the 2w1 sp/sx had a strong worrier streak to him, an anxiety about things being "just right". Unlike the sp-1 he didn't hide that aspect of himself - he did not care about being seen as competent and having everything under control - and very easily shared his worries and anxieties with people around him, graciously accepting their advice and help. His 1-wing was easily extraverted, and made for almost like a social pastime to him, a basis on which he connected to others.
Naranjo describes sp-2 as being similar to a child in their seductive qualities, and this is how he was. Behind the critical "lets get everything right" was a call of "love me" and "take care of me". (Naranjo Self Preservation 2s “seduce” like a child in the presence of grown-ups as a way of (unconsciously) inducing others to take care of them. Everyone likes children, and the Sp 2 adopts a youthful stance as a way of getting special treatment well beyond childhood. As the countertype, it’s less easy to see pride in this 2 because they are more fearful of and ambivalent about connecting with others. The title “Privilege” reflects this 2’s desire to be loved and prioritized just for being who they are, not for what they give to others. Related to the youthful stance, these 2s are playful, irresponsible and charming.)
The 2w1 sx/sp was very different, much more confident and competitive, especially when it came to her own feelings and her relationships with others, but just as desiring of love as the sp-2. She would try to win over people's love in an almost imposing way, and if she couldn't get their love as least demand their gratitude. Less worrying about the details, more of assertive, emotionally unstable energy. When she was trying to win someone over, she would hone into their needs and then do everything in her powers to satisfy them, and do so better than her "rivals" could do it for that person. This sometimes turned into projects that she would take up for 2+ years. At the same time, she would forget about her own needs, which was strange to witness.
Her critical side showed up as commentary about people's characters: who was a "good person" who "acted right" and who was a "bad apple" and behaved "badly". She never used the words good/bad herself and her evaluations were situationally nuanced, but if it had to be summarized that's how it was.
The few 2w3s I've seen around appeared to have more polish and suaveness to themselves in comparison to 2w1s. The 2w1s seemed to be always "going against the grain" somehow, never fully pacified or quieted down (double superego type), with the need to challenge or go against something (1s pull away). The 2w3s had a smooth velvety feel to them and none of the same prickliness of 2w1s.